Treg-Resistant Cytotoxic CD4(+) T Cells Dictate T Helper Cells in Their Vicinity: TH17 Skewing and Modulation of Proliferation

Hoeks, C; Vanheusden, M; Peeters, LM; Stinissen, P; Broux, B; Hellings, N

Hellings, N (corresponding author), Hasselt Univ, Biomed Res Inst, Dept Immunol & Infect, Neuro Immune Connect & Repair Lab, Martelarenlaan 42, B-3500 Hasselt, Belgium.; Hellings, N (corresponding author), Univ MS Ctr UMSC, Martelarenlaan 42, B-3500 Hasselt, Belgium.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021; 22 (11):

Abstract

Cytotoxic CD4(+) T cells (CD4 CTL) are terminally differentiated T helper cells that contribute to autoimmune diseases, such as multiple sclerosis. We......

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