Multiple microRNAs regulate tacrolimus metabolism through CYP3A5

Gu, XQ; Tang, D; Wan, P; Qin, T; Yang, TH; Wu, J; Ji, H; Liu, JC; Xue, F; Tang, YJ; Xia, Q

Xue, F (corresponding author), Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Dept Liver Surg, Shanghai 200127, Peoples R China.; Tang, YJ (corresponding author), Shanghai Jiao Tong Univ, Renji Hosp, Sch Med, Shanghai Inst Rheumatol, Shanghai, Peoples R China.

PHARMACOLOGICAL RESEARCH, 2021; 164 ():

Abstract

The CYP3A5 gene polymorphism accounts for the majority of inter-individual variability in tacmlimus pharmacokinetics. We found that the basal expressi......

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