IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease

Dambuza, IM; He, C; Choi, JK; Yu, CR; Wang, RX; Mattapallil, MJ; Wingfield, PT; Caspi, RR; Egwuagu, CE

Egwuagu, CE (reprint author), NEI, Mol Immunol Sect, Immunol Lab, NIH, Bethesda, MD 20892 USA.

NATURE COMMUNICATIONS, 2017; 8 ( ):

Abstract

Interleukin 35 (IL-35) is a heterodimeric cytokine composed of IL-12p35 and Ebi3 subunits. IL-35 suppresses autoimmune diseases while preventing host ......

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