Alternative regulation of HIF-1 alpha stability through Phosphorylation on Ser451

Han, HJ; Saeidi, S; Kim, SJ; Piao, JY; Lim, S; Guillen-Quispe, YN; Choi, BY; Surh, YJ

Surh, YJ (corresponding author), Seoul Natl Univ, Coll Pharm, 1 Gwanak Ro, Seoul 151742, South Korea.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021; 545 (): 150

Abstract

The hypoxia-inducible factor (HIF-1 alpha) functions as a master regulator of oxygen homeostasis. Oxygen dependent hydroxylation of HIF-1 alpha is tig......

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