High-Throughput Fluorescence-Based Activity Assay for Arginase-1

Grobben, Y; Willemsen-Seegers, N; Uitdehaag, JCM; de Man, J; van Groningen, J; Friesen, J; van den Hurk, H; Buijsman, RC; Zaman, GJR

Zaman, GJR (corresponding author), Netherlands Translat Res Ctr BV, Kloosterstr 9, NL-5349 AB Oss, Netherlands.

SLAS DISCOVERY, 2020; 25 (9): 1018

Abstract

Arginase-1, which converts the amino acid L-arginine into L-ornithine and urea, is a promising new drug target for cancer immunotherapy, as it has a r......

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