Target-mediated drug disposition modeling of an anti-TFPI antibody (MG1113) in cynomolgus monkeys to predict human pharmacokinetics and pharmacodynamics

Kwak, EY; Kim, MJ; Park, JH; Jung, H; Jung, ME

Jung, ME (corresponding author), DIGMBIO, Bio Div, 9-22,Pangyo Ro 255Beon Gil, Seongnam Si 13486, Gyeonggi Do, South Korea.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2021; 19 (6): 1425

Abstract

Background MG1113 is a human monoclonal antibody of tissue factor pathway inhibitor (TFPI) under development for prophylaxis for hemophilia patients w......

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