Polycyclic phloroglucinols as PTP1B inhibitors from Hypericum longistylum: Structures, PTP1B inhibitory activities, and interactions with PTP1B

Cao, XR; Yang, XY; Wang, PX; Liang, Y; Liu, F; Tuerhong, M; Jin, DQ; Xu, J; Lee, D; Ohizumi, Y; Guo, YQ

Xu, J; Guo, YQ (reprint author), Nankai Univ, State Key Lab Med Chem Biol, Coll Pharm, Tianjin 300071, Peoples R China.; Xu, J; Guo, YQ (reprint author), Nankai Univ, Tianjin Key Lab Mol Drug Res, Tianjin 300071, Peoples R China.

BIOORGANIC CHEMISTRY, 2017; 75 ( ): 139

Abstract

Protein tyrosine phosphatase 1B (PTP1B) has been regarded as a target for the research and development of new drugs to treat type II diabetes and PTP1......

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