Engineered Biosynthesis of 5/5/6 Type Polycyclic Tetramate Macrolactams in an Ikarugamycin (5/6/5 Type)-Producing Chassis

Jin, HB; Zhang, WJ; Zhang, GT; Zhang, LP; Liu, W; Zhang, CS

ORGANIC LETTERS, 2020; 22 (5): 1731

Abstract

Combinatorial biosynthesis of 5/5/6 type polycyclic tetramate macrolactams (PoTeMs) was achieved in an engineered ikarugamycin (5/6/5 type) producer b......

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