Neuroprotective effect of selumetinib on acrolein-induced neurotoxicity

Huang, HJ; Wang, HT; Yeh, TY; Lin, BW; Shiao, YJ; Lo, YL; Lin, AMY

Lin, AMY (corresponding author), Taipei Vet Gen Hosp, Dept Med Res, Taipei, Taiwan.; Lo, YL; Lin, AMY (corresponding author), Natl Yang Ming Chiao Tung Univ, Inst Pharmacol, Taipei, Taiwan.; Lin, AMY (corresponding author), Natl Yang Ming Chiao Tung Univ, Dept Pharm, Taipei, Taiwan.

SCIENTIFIC REPORTS, 2021; 11 (1):

Abstract

Abnormal accumulation of acrolein, an alpha, beta unsaturated aldehyde has been reported as one pathological cause of the CNS neurodegenerative diseas......

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