Alisertib exerts KRAS allele-specific anticancer effects on colorectal cancer cell lines

Ren, BJ; Geng, Y; Chen, SX; Gao, ZW; Zheng, KH; Yang, Y; Luo, QM; Feng, J; Luo, ZT; Ju, YL; Huang, ZH

Ju, YL (通讯作者)，Southern Med Univ, Dept Gastrointestinal Surg, Shunde Hosp, Peoples Hosp Shunde 1,Sch Clin Med 2, 1 Jiazi Rd, Foshan 528308, Guangdong, Peoples R China.;Huang, ZH (通讯作者)，Southern Med Univ, Dept Gen Surg, Zhujiang Hosp, Sch Clin Med 2, 253 Ind Ave, Guangzhou 510280, Guangdong, Peoples R China.

EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2023; 25 (6):

Abstract

The aim of the present study was to examine the effects of alisertib (ALS) on RAS signaling pathways against a panel of colorectal cancer (CRC) cell l......

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