Cytosolic Fe-superoxide dismutase safeguards Trypanosoma cruzi from macrophage-derived superoxide radical

Martinez, A; Prolo, C; Estrada, D; Rios, N; Alvarez, MN; Pineyro, MD; Robello, C; Radi, R; Piacenza, L

Radi, R; Piacenza, L (reprint author), Univ Republica, Fac Med, Dept Bioquim, Montevideo 11800, Uruguay.; Radi, R; Piacenza, L (reprint author), Univ Republica, Fac Med, Ctr Invest Biomed CEINBIO, Montevideo 11800, Uruguay.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019; 116 (18): 8879

Abstract

Trypanosoma cruzi, the causative agent of Chagas disease (CD), contains exclusively Fe-dependent superoxide dismutases (Fe-SODs). During T. cruzi inva......

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