Crystal structure of a lipin/Pah phosphatidic acid phosphatase

Khayyo, VI; Hoffmann, RM; Wang, H; Bell, JA; Burke, JE; Reue, K; Airola, MVV

Airola, MVV (corresponding author), SUNY Stony Brook, Dept Biochem & Cell Biol, Stony Brook, NY 11794 USA.

NATURE COMMUNICATIONS, 2020; 11 (1):

Abstract

Lipin/Pah phosphatidic acid phosphatases (PAPs) generate diacylglycerol to regulate triglyceride synthesis and cellular signaling. Inactivating mutati......

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