Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease

Zhou, XG; Qiu, WQ; Yu, L; Pan, R; Teng, JF; Sang, ZP; Law, BYK; Zhao, Y; Zhang, L; Yan, L; Tang, Y; Sun, XL; Wong, VKW; Yu, CL; Wu, JM; Qin, DL; Wu, AG

Wu, JM; Qin, DL; Wu, AG (通讯作者)，Southwest Med Univ, Sch Pharm,Minist Educ,Key Lab Med Electrophysiol, Sichuan Key Med Lab New Drug Discovery & Drugabil, Luzhou Key Lab Act Screening & Druggabil Evaluat, Luzhou 646000, Peoples R China.

INFLAMMATION AND REGENERATION, 2022; 42 (1):

Abstract

Background NLRP3 inflammasome-mediated neuroinflammation plays a critical role in the pathogenesis and development of Alzheimer's disease (AD). Microg......

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