Targeting Super-Enhancer-Driven Oncogenic Transcription by CDK7 Inhibition in Anaplastic Thyroid Carcinoma

Cao, XY; Dang, L; Zheng, XQ; Lu, Y; Lu, YM; Ji, RJ; Zhang, TY; Ruan, XH; Zhi, JT; Hou, XK; Yi, XF; Li, MLJ; Gu, TY; Gao, M; Zhang, LR; Chen, YP

Gao, M (reprint author), Tianjin Med Univ Canc Inst & Hosp, Oncol Key Lab Canc Prevent & Therapy, Natl Clin Res Ctr Canc, Dept Thyroid & Neck Tumor, Tianjin 300060, Peoples R China.; Zhang, LR; Chen, YP (reprint author), Tianjin Med Univ, Sch Basic Med Sc

THYROID, 2019; 29 (6): 809

Abstract

Background: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive malignancies, with no effective treatment currently available. The molecu......

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