Synthesis and Biological Evaluation of 5-benzyl-3-pyridyl-1H-1,2,4-triazole Derivatives as Xanthine Oxidase Inhibitors

Li, SY; Zhang, TJ; Wu, QX; Olounfeh, KM; Zhang, Y; Meng, FH

Meng, FH (corresponding author), China Med Univ, Sch Pharm, 77 Puhe Rd,North New Area, Shenyang 110122, Peoples R China.

MEDICINAL CHEMISTRY, 2020; 16 (1): 119

Abstract

Background: Topiroxostat is an excellent xanthine oxidase (XO) inhibitor, possessing a specific 3,5-diaryl-1,2,4-triazole framework. Objective: The pr......

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