Targeting tauopathy with engineered tau-degrading intrabodies

Gallardo, G; Wong, CH; Ricardez, SM; Mann, CN; Lin, KH; Leyns, CEG; Jiang, H; Holtzman, DM

Gallardo, G; Holtzman, DM (reprint author), Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA.

MOLECULAR NEURODEGENERATION, 2019; 14 (1):

Abstract

Background The accumulation of pathological tau is the main component of neurofibrillary tangles and other tau aggregates in several neurodegenerative......

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