The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway

Ogishima, J; Taguchi, A; Kawata, A; Kawana, K; Yoshida, M; Yoshimatsu, Y; Sato, M; Nakamura, H; Kawata, Y; Nishijima, A; Fujimoto, A; Tomio, K; Adachi, K; Nagamatsu, T; Oda, K; Kiyono, T; Osuga, Y; Fujii, T

Taguchi, A (reprint author), Univ Tokyo, Grad Sch Med, Dept Obstet & Gynecol, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan.; Kawana, K (reprint author), Nihon Univ, Grad Sch Med, Dept Obstet & Gynecol, Itabashi Ku, 30-1 Otaniguchi Uemachi, Tokyo 1738610,

BMC CANCER, 2018; 18 ():

Abstract

BackgroundPeritoneal dissemination is a critical prognostic factor in ovarian cancer. Although stabilized spheroid formation promotes cancer cell peri......

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