Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site

Vogeli, B; Engilberge, S; Girard, E; Riobe, F; Maury, O; Erb, TJ; Shima, S; Wagner, T

Wagner, T (reprint author), Max Planck Inst Terr Microbiol, Microbial Prot Struct Grp, D-35043 Marburg, Germany.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018; 115 (13): 3380

Abstract

Many reactions within a cell are thermodynamically unfavorable. To efficiently run some of those endergonic reactions, nature evolved intermediate-cha......

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