Aristolochic acid I induces impairment in spermatogonial stem cell in rodents

Liu, YZ; He, X; Wang, YL; Zhou, HZ; Zhang, Y; Ma, JY; Wang, ZC; Yang, FF; Lu, HL; Yang, YF; Deng, ZP; Qi, XM; Gong, LK; Ren, J

Deng, ZP (corresponding author), Shanghai Univ Tradit Chinese Med, Ctr Drug Safety Evaluat & Res, Innovat Res Inst Tradit Chinese Med, 1200 Cailun Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China.; Qi, XM; Gong, LK; Ren, J (corresponding author), Chinese Acad Sci, Ctr Drug Safety Evaluat & Res, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China.; Gong, LK (corresponding author), Chinese Acad Sci, Zhongshan Inst Drug Discove

TOXICOLOGY RESEARCH, 2021; 10 (3): 436

Abstract

Aristolochic acid I (AAI) is a natural bioactive substance found in plants from the Aristolochiaceae family and impairs spermatogenesis. However, whet......

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