MRE11 UFMylation promotes ATM activation

Wang, ZF; Gong, YM; Peng, B; Shi, RF; Fan, D; Zhao, HC; Zhu, M; Zhang, HX; Lou, ZK; Zhou, JW; Zhu, WG; Cong, YS; Xu, XZ

Xu, XZ (reprint author), Shenzhen Univ, Sch Med, Guangdong Key Lab Genome Stabil & Dis Prevent, Shenzhen 518060, Guangdong, Peoples R China.; Zhou, JW (reprint author), Nanjing Med Univ, Dept Mol Cell Biol & Toxicol, Sch Publ Hlth, Nanjing 211166, Jiangsu

NUCLEIC ACIDS RESEARCH, 2019; 47 (8): 4124

Abstract

A proper DNA damage response (DDR) is essential to maintain genome integrity and prevent tumorigenesis. DNA double-strand breaks (DSBs) are the most t......

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