Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling

Guo, GJ; Gao, M; Gao, XC; Zhu, BB; Huang, JZ; Tu, XY; Kim, W; Zhao, F; Zhou, Q; Zhu, SH; Wu, ZM; Yan, YL; Zhang, Y; Zeng, XY; Zhu, Q; Yin, P; Luo, KT; Sun, J; Deng, M; Lou, ZK

Deng, M; Lou, ZK (corresponding author), Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN 55905 USA.; Deng, M; Lou, ZK (corresponding author), Mayo Clin, Dept Oncol, Rochester, MN 55905 USA.

NATURE COMMUNICATIONS, 2021; 12 (1):

Abstract

The RNA-sensing pathway contributes to type I interferon (IFN) production induced by DNA damaging agents. However, the potential involvement of RNA se......

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