Itraconazole-Induced Increases in Gilteritinib Exposure Are Mediated by CYP3A and OATP1B

Garrison, DA; Jin, Y; Talebi, Z; Hu, SY; Sparreboom, A; Baker, SD; Eisenmann, ED

Eisenmann, ED (通讯作者)，Ohio State Univ, Div Pharmaceut & Pharmacol, Columbus, OH 43210 USA.

MOLECULES, 2022; 27 (20):

Abstract

Gilteritinib, an FDA-approved tyrosine kinase inhibitor approved for the treatment of relapsed/refractory FLT3-mutated acute myeloid leukemia, is prim......

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