Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Loftus, RM; Assmann, N; Kedia-Mehta, N; O'Brien, KL; Garcia, A; Gillespie, C; Hukelmann, JL; Oefner, PJ; Lamond, AI; Gardiner, CM; Dettmer, K; Cantrell, DA; Sinclair, LV; Finlay, DK

Finlay, DK (reprint author), Trinity Coll Dublin, Sch Biochem & Immunol, Trinity Biomed Sci Inst, 152-160 Pearse St, Dublin 2, Ireland.; Finlay, DK (reprint author), Trinity Coll Dublin, Sch Pharm & Pharmaceut Sci, Trinity Biomed Sci Inst, 152-160 Pearse

NATURE COMMUNICATIONS, 2018; 9 ():

Abstract

Natural killer (NK) cells are lymphocytes with important anti-tumour functions. Cytokine activation of NK cell glycolysis and oxidative phosphorylatio......

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