TET1 downregulates epithelial-mesenchymal transition and chemoresistance in PDAC by demethylating CHL1 to inhibit the Hedgehog signaling pathway

Li, H; Jiang, W; Liu, XN; Yuan, LY; Li, TJ; Li, S; Xu, SS; Zhang, WH; Gao, HL; Han, X; Wang, WQ; Wu, CT; Yu, XJ; Xu, HX; Liu, L

Yu, XJ; Xu, HX; Liu, L (corresponding author), Fudan Univ, Shanghai Canc Ctr, Dept Pancreat Surg, Shanghai, Peoples R China.; Yu, XJ; Xu, HX; Liu, L (corresponding author), Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai, Peoples R China.; Yu, XJ; Xu, HX; Liu, L (corresponding author), Shanghai Pancreat Canc Inst, Shanghai, Peoples R China.; Yu, XJ; Xu, HX; Liu, L (corresponding author), Fudan Univ, Pancreat Canc Inst, Shanghai, Peoples R China.

ONCOGENE, 2020; 39 (36): 5825

Abstract

Chemoresistance is a major obstacle to prolonging pancreatic ductal adenocarcinoma (PDAC) patient survival. TET1 is identified as the most important e......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索