BBS Proteins Affect Ciliogenesis and Are Essential for Hedgehog Signaling, but Not for Formation of iPSC-Derived RPE-65 Expressing RPE-Like Cells

Hey, CAB; Larsen, LJ; Tumer, Z; Brondum-Nielsen, K; Gronskov, K; Hjortshoj, TD; Moller, LB

Moller, LB (corresponding author), Rigshosp, Copenhagen Univ Hosp, Dept Clin Genet, Gl Landevej 7, DK-2600 Glostrup, Denmark.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021; 22 (3):

Abstract

Bardet-Biedl syndrome (BBS) is a ciliopathy characterized by retinal dystrophy, renal cysts, obesity and polydactyly. BBS genes have been implicated i......

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