Caspase-8 restricts antiviral CD8 T cell hyperaccumulation

Feng, YJ; Daley-Bauer, LP; Roback, L; Guo, HY; Koehler, HS; Potempa, M; Lanier, LL; Mocarski, ES

Mocarski, ES (reprint author), Emory Univ, Sch Med, Dept Microbiol & Immunol, Emory Vaccine Ctr, Atlanta, GA 30033 USA.; Lanier, LL (reprint author), Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA.; Lanier, LL (reprint aut

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019; 116 (30): 15170

Abstract

The magnitude of CD8 T cell responses against viruses is checked by the balance of proliferation and death. Caspase-8 (CASP8) has the potential to inf......

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