Targeting PGAM1 in cancer: An emerging therapeutic opportunity

Yang, GJ; Tao, F; Zhong, HJ; Yang, C; Chen, J

Chen, J (通讯作者)，Ningbo Univ, State Key Lab Managing Biot & Chem Threats Qual &, Ningbo 315211, Zhejiang, Peoples R China.;Zhong, HJ (通讯作者)，Jinan Univ, Inst New Drug Res, Coll Pharm, Guangzhou 510632, Peoples R China.;Zhong, HJ (通讯作者)，Jinan Univ Coll Pharm, Guangdong Prov Key Lab Pharmacodynam Constituents, Guangzhou 510632, Peoples R China.;Yang, C (通讯作者)，Zhejiang Ocean Univ, Inst Innovat & Applicat, Natl Engn Res Ctr Marine Aquaculture, Zhoushan 316022, Zhejiang, Peoples R China.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022; 244 ():

Abstract

Glycolysis is a preferred metabolic pattern of cancer cells. Phosphoglycerate mutase 1 (PGAM1) is a pivotal glycolytic enzyme that catalyzes the recip......

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