Identification of a point mutation PMLS214L-RAR alpha that alters PML body organization, dynamics and SUMOylation

Zhao, SS; Shi, P; Zhong, QH; Shao, SP; Huang, YX; Sun, YJ; Wu, CY; Zhu, HH

Wu, CY (reprint author), Peking Univ, Sch Basic Med Sci, Inst Syst Biomed, Hlth Sci Ctr, Beijing 100191, Peoples R China.; Sun, YJ (reprint author), Peking Univ, Sch Life Sci, Biodynam Opt Imaging Ctr BIOPIC, State Key Lab Membrane Biol, Beijing 100871, P

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019; 511 (3): 518

Abstract

Genetic mutations on PML-RAR alpha in acute promyelocytic leukemia (APL) are reported to associate with arsenic trioxide (ATO) or all-trans retinoic a......

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