RUNX3 improves CAR-T cell phenotype and reduces cytokine release while maintaining CAR-T function

Zhu, XX; Li, WL; Gao, JD; Shen, JJ; Xu, YM; Zhang, CC; Qian, C

Qian, C (通讯作者),Chongqing Univ, Coll Bioengn, Chongqing, Peoples R China.;Zhang, CC; Qian, C (通讯作者),Army Med Univ, Southwest Hosp, Ctr Biotherapy, Chongqing, Peoples R China.;Qian, C (通讯作者),Chongqing Univ, Ctr Precis Med Canc, Chongqing Key Lab Translat Res Canc Metastasis & I, Canc Hosp, Chongqing 400030, Peoples R China.

MEDICAL ONCOLOGY, 2023; 40 (3):

Abstract

CAR-T therapy has shown successful in the treatment of certain types of hematological malignancy, while the efficacy of CAR-T cell in treating solid t......

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