New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2

Salomatina, OV; Dyrkheeva, NS; Popadyuk, II; Zakharenko, AL; Ilina, ES; Komarova, NI; Reynisson, J; Salakhutdinov, NF; Lavrik, OI; Volcho, KP

Volcho, KP (通讯作者),SB RAS, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Lavrentev Ave, Novosibirsk 630090, Russia.

MOLECULES, 2022; 27 (1):

Abstract

A series of deoxycholic acid (DCA) amides containing benzyl ether groups on the steroid core were tested against the tyrosyl-DNA phosphodiesterase 1 (......

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