New Highly Selective BACE1 Inhibitors and Their Effects on Dendritic Spine Density In Vivo

Pratsch, K; Unemura, C; Ito, M; Lichtenthaler, SF; Horiguchi, N; Herms, J

Herms, J (通讯作者),German Ctr Neurodegenerat Dis DZNE, D-81377 Munich, Germany.;Herms, J (通讯作者),Munich Cluster Syst Neurol SyNergy, D-81377 Munich, Germany.;Herms, J (通讯作者),Ludwig Maximilians Univ Munchen, Fac Med, Ctr Neuropathol & Pr Res ZNP, D-81377 Munich, Germany.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (15):

Abstract

& beta;-site amyloid precursor protein-cleaving enzyme 1 (BACE1) is considered a therapeutic target to combat Alzheimer's disease by reducing &amp......

Full Text Link