Discovery of novel JAK2 and EGFR inhibitors from a series of thiazole-based chalcone derivatives

Sanachai, K; Aiebchun, T; Mahalapbutr, P; Seetaha, S; Tabtimmai, L; Maitarad, P; Xenikakis, I; Geronikaki, A; Choowongkomon, K; Rungrotmongkol, T

Rungrotmongkol, T (corresponding author), Chulalongkorn Univ, Fac Sci, Dept Biochem, Struct & Computat Biol Res Unit, Bangkok 10330, Thailand.; Rungrotmongkol, T (corresponding author), Chulalongkorn Univ, Grad Sch, Program Bioinformat & Computat Biol, Bangkok 10330, Thailand.

RSC MEDICINAL CHEMISTRY, 2021; 12 (3): 430

Abstract

The Janus kinase (JAK) and epidermal growth factor receptor (EGFR) have been considered as potential targets for cancer therapy due to their role in r......

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