Interleukin-7 receptor blockade by an anti-CD127 monoclonal antibody in nonhuman primate kidney transplantation

Mai, HL; Nguyen, TVH; Branchereau, J; Poirier, N; Renaudin, K; Mary, C; Belarif, L; Minault, D; Hervouet, J; Le Bas-Berdardet, S; Soulillou, JP; Vanhove, B; Blancho, G; Brouard, S

Mai, HL (reprint author), Univ Nantes, CRTI, INSERM, UMR 1064, Nantes, France.; Mai, HL (reprint author), CHU Nantes, ITUN, Nantes, France.

AMERICAN JOURNAL OF TRANSPLANTATION, 2020; 20 (1): 101

Abstract

IL-7 is an important cytokine for T cell lymphopoiesis. Blockade of the IL-7 signaling pathway has been shown to induce long-term graft survival or gr......

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