Amyloid-beta Inhibits PDGF beta Receptor Activation and Prevents PDGF-BB-induced Neuroprotection

Liu, H; Saffi, GT; Vasefi, MS; Choi, Y; Kruk, JS; Ahmed, N; Gondora, N; Mielke, J; Leonenko, Z; Beazely, MA

Beazely, MA (reprint author), Univ Waterloo, Sch Pharm, Fac Sci, 10 Victoria St South, Kitchener, ON N2G 1C5, Canada.

CURRENT ALZHEIMER RESEARCH, 2018; 15 (7): 618

Abstract

Background: PDGF beta receptors and their ligand, PDGF-BB, are upregulated in vivo after neu-ronal insults such as ischemia. When applied exogenously,......

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