MicroRNAs target the PI3K/Akt/p53 and the Sirt1/Nrf2 signaling pathways in doxorubicin-induced cardiotoxicity

Yarmohammadi, F; Ebrahimian, Z; Karimi, G

Karimi, G (通讯作者),Mashhad Univ Med Sci, Pharmaceut Technol Inst, Pharmaceut Res Ctr, Mashhad, Iran.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2023; 37 (2):

Abstract

Doxorubicin (DOX) is used as a chemotherapeutic agent in the treatment of solid tumors. Irreversible cardiotoxicity is the major limitation in the cli......

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