IL-33 enhances macrophage release of IL-1 beta and promotes pain and inflammation in gouty arthritis

Fattori, V; Staurengo-Ferrari, L; Zaninelli, TH; Casagrande, R; Oliveira, RD; Louzada, P; Cunha, TM; Alves, JC; Teixeira, MM; Cunha, FQ; Amaral, FA; Verri, WA

Verri, WA (corresponding author), Univ Estadual Londrina, Dept Pathol, Lab Pain Inflammat Neuropathy & Canc, Londrina, Parana, Brazil.; Verri, WA (corresponding author), Univ Estadual Londrina, Ctr Ciencias Biol, Dept Ciencias Patol, Rodovia Celso Garcia Cid,PR 445,KM 380,POB 10-011, BR-86057970 Londrina, PR, Brazil.

INFLAMMATION RESEARCH, 2020; 69 (12): 1271

Abstract

Objective To investigate the role of IL-33 in gouty arthritis. Material 174 Balb/c (wild-type) and 54 ST2(-/-)mice were used in this study. In vitro e......

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