CXCR4 blockade sensitizes osteosarcoma to doxorubicin by inducing autophagic cell death via PI3K-Akt-mTOR pathway inhibition-MedSci.cn

CXCR4 blockade sensitizes osteosarcoma to doxorubicin by inducing autophagic cell death via PI3K-Akt-mTOR pathway inhibition

Liao, YX; Lv, JY; Zhou, ZF; Xu, TY; Yang, D; Gao, QM; Fan, L; Li, GD; Yu, HY; Liu, KY

Yu, HY; Liu, KY (corresponding author), Tongji Univ, Shanghai Tenth Peoples Hosp, Dept Orthopaed, Sch Med, 301 Yanchang Rd, Shanghai 200072, Peoples R China.

INTERNATIONAL JOURNAL OF ONCOLOGY, 2021; 59 (1):

Abstract

Doxorubicin is one of the most frequently used chemotherapy drugs in the treatment of osteosarcoma (OS), but the emergence of chemoresistance often le......

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