Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ-TEAD Biosensors

Nouri, K; Azad, T; Ling, M; van Rensburg, HJJ; Pipchuk, A; Shen, H; Hao, YW; Zhang, JM; Yang, XL

Yang, XL (reprint author), Queens Univ, Dept Pathol & Mol Med, Kingston, ON K7L 3N6, Canada.

CANCERS, 2019; 11 (10):

Abstract

The Hippo pathway has emerged as a key signaling pathway that regulates a broad range of biological functions, and dysregulation of the Hippo pathway ......

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