Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells

Zhao, YL; Harrison, DL; Song, YR; Ji, J; Huang, J; Hui, EF

Hui, EF (reprint author), Univ Calif San Diego, Div Biol Sci, Sect Cell & Dev Biol, La Jolla, CA 92093 USA.

CELL REPORTS, 2018; 24 (2): 379

Abstract

The PD-1 pathway, consisting of the co-inhibitory receptor PD-1 on T cells and its ligand (PD-L1) on antigen- presenting cells (APCs), is a major mech......

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