Regulation of a PRMT5/NF-kappa B Axis by Phosphorylation of PRMT5 at Serine 15 in Colorectal Cancer

Hartley, AV; Wang, BL; Jiang, GL; Wei, H; Sun, MY; Prabhu, L; Martin, M; Safa, A; Sun, S; Liu, YL; Lu, T

Lu, T (corresponding author), Indiana Univ Sch Med, Dept Pharmacol & Toxicol, 635 Barnhill Dr, Indianapolis, IN 46202 USA.; Lu, T (corresponding author), Indiana Univ Sch Med, Dept Biochem & Mol Biol, 635 Barnhill Dr, Indianapolis, IN 46202 USA.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020; 21 (10):

Abstract

The overexpression of PRMT5 is highly correlated to poor clinical outcomes for colorectal cancer (CRC) patients. Importantly, our previous work demons......

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