Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches

Kaan, HYK; Sim, AYL; Tan, SKJ; Verma, C; Song, HW

Song, HW (reprint author), ASTAR, Inst Mol & Cell Biol, 61 Biopolis Dr, Singapore, Singapore.; Verma, C (reprint author), ASTAR, Bioinformat Inst, Singapore, Singapore.; Verma, C (reprint author), Natl Univ Singapore, Dept Biol Sci, 14 Sci Dr 4, Singapore

PLOS ONE, 2017; 12 (6):

Abstract

The Hippo signaling pathway, which is implicated in the regulation of organ size, has emerged as a potential target for the development of cancer ther......

Full Text Link