Fortilin binds IRE1 alpha and prevents ER stress from signaling apoptotic cell death

Pinkaew, D; Chattopadhyay, A; King, MD; Chunhacha, P; Liu, ZH; Stevenson, HL; Chen, YJ; Sinthujaroen, P; McDougal, OM; Fujise, K

Fujise, K (reprint author), Univ Texas Med Branch, Dept Internal Med, Div Cardiol, Galveston, TX 77555 USA.; Fujise, K (reprint author), Univ Texas Med Branch, Dept Biochem & Mol Biol, Galveston, TX 77555 USA.; Fujise, K (reprint author), Univ Texas Med B

NATURE COMMUNICATIONS, 2017; 8 ( ):

Abstract

The endoplasmic reticulum, the cytoplasmic organelle that matures a massive amount of nascent secretory polypeptides, is particularly sensitive to str......

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