Targeting CD4(+) Cells with Anti-CD4 Conjugated Mertansine-Loaded Nanogels

Canakci, M; Singh, K; Munkhbat, O; Shanthalingam, S; Mitra, A; Gordon, M; Osborne, BA; Thayumanavan, S

Osborne, BA (corresponding author), Univ Massachusetts, Dept Vet & Anim Sci, Amherst, MA 10003 USA.; Osborne, BA; Thayumanavan, S (corresponding author), Univ Massachusetts, Mol & Cellular Biol Program, Amherst, MA 10003 USA.; Osborne, BA; Thayumanavan, S (corresponding author), Univ Massachusetts, Ctr Bioact Delivery, Inst Appl Life Sci, Amherst, MA 01003 USA.; Thayumanavan, S (corresponding author), Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA.

BIOMACROMOLECULES, 2020; 21 (6): 2473

Abstract

CD4(+) T lymphocytes play an important role in controlling many malignancies. The modulation of CD4(+) T cells through immunomodulatory or cytotoxic d......

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