USP10 deubiquitinates Tau, mediating its aggregation

Wei, Z; Zeng, K; Hu, JC; Li, X; Huang, F; Zhang, B; Wang, JZ; Liu, R; Li, HL; Wang, XC

Li, HL; Wang, XC (通讯作者)，Huazhong Univ Sci & Technol, Tongji Med Coll, Hubei Prov China Neurol Disorders, Dept Pathophysiol,Sch Basic Med,Key Lab,Educ Mini, Wuhan, Peoples R China.;Wang, XC (通讯作者)，Nantong Univ, Coinnovat Ctr Neuroregenerat, Nantong, JS, Peoples R China.;Wang, XC (通讯作者)，Jianghan Univ, Sch Med, Dept Pathol & Pathophysiol, Wuhan, Peoples R China.;Wang, XC (通讯作者)，Shenzhen Huazhong Univ Sci & Technol Res Inst, Shenzhen, Peoples R China.

CELL DEATH & DISEASE, 2022; 13 (8):

Abstract

Normal Tau promotes the assembly and stabilization of microtubules, thus, maintaining axon transport. In Alzheimer's disease (AD), Tau aggregation cau......

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