Thrombomodulin ameliorates transforming growth factor-beta 1-mediated chronic kidney disease via the G-protein coupled receptor 15/Akt signal pathway

Takeshita, A; Yasuma, T; Nishihama, K; D'Alessandro-Gabazza, CN; Toda, M; Totoki, T; Okano, Y; Uchida, A; Inoue, R; Qin, LQ; Wang, SJ; D'Alessandro, VF; Kobayashi, T; Takei, Y; Mizoguchi, A; Yano, Y; Gabazza, EC

Gabazza, EC (corresponding author), Mie Univ, Grad Sch Med, Dept Immunol, Edobashi 2-174, Tsu, Mie 5148507, Japan.; Yano, Y (corresponding author), Mie Univ, Grad Sch Med, Diabet Metab & Endocrinol, Edobashi 2-774, Tsu, Mie 5148507, Japan.

KIDNEY INTERNATIONAL, 2020; 98 (5): 1179

Abstract

Kidney fibrosis is the common consequence of chronic kidney diseases that inexorably progresses to end-stage kidney disease with organ failure treatab......

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