Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone

Ryder, BD; Matlahov, I; Bali, S; Vaquer-Alicea, J; van der Wel, PCA; Joachimiak, LA

Joachimiak, LA (corresponding author), Univ Texas Southwestern Med Ctr Dallas, Ctr Alzheimers & Neurodegenerat Dis, Dallas, TX 75390 USA.; van der Wel, PCA (corresponding author), Univ Pittsburgh, Sch Med, Dept Struct Biol, Pittsburgh, PA 15260 USA.; van der Wel, PCA (corresponding author), Univ Groningen, Zernike Inst Adv Mat, Groningen, Netherlands.; Joachimiak, LA (corresponding author), Univ Texas Southwestern Med Ctr Dallas, Dept Biochem, Dallas, TX 75390 USA.

NATURE COMMUNICATIONS, 2021; 12 (1):

Abstract

The Hsp40/Hsp70 chaperone families combine versatile folding capacity with high substrate specificity, which is mainly facilitated by Hsp40s. The stru......

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