A Chimeric Egfr Protein Reporter Mouse Reveals Egfr Localization and Trafficking In Vivo

Yang, YP; Ma, HT; Starchenko, A; Huh, WJ; Li, W; Hickman, FE; Zhang, Q; Franklin, JL; Mortlock, DP; Fuhrmann, S; Carter, BD; Ihrie, RA; Coffey, RJ

Coffey, RJ (reprint author), Vanderbilt Univ, Med Ctr, Dept Med, Nashville, TN 37232 USA.; Coffey, RJ (reprint author), Vanderbilt Univ, Med Ctr, Epithelial Biol Ctr, Nashville, TN 37232 USA.; Coffey, RJ (reprint author), Vanderbilt Univ, Dept Cell & Dev

CELL REPORTS, 2017; 19 (6): 1257

Abstract

EGF receptor (EGFR) is a critical signaling node throughout life. However, it has not been possible to directly visualize endogenous Egfr in mice. Usi......

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