Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin

Wijshake, T; Zou, ZJ; Chen, BB; Zhong, L; Xiao, GH; Xie, Y; Doench, JG; Bennett, L; Levine, B

Bennett, L (corresponding author), Univ Texas Southwestern Med Ctr Dallas, Ctr Autophagy Res, Dallas, TX 75390 USA.; Bennett, L (corresponding author), Univ Texas Southwestern Med Ctr Dallas, Dept Internal Med, Dallas, TX 75390 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021; 118 (5):

Abstract

Beclin 1, an autophagy and haploinsufficient tumor-suppressor protein, is frequently monoallelically deleted in breast and ovarian cancers. However, t......

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