Efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in nasopharyngeal carcinoma in vitro and in vivo

Huang, Y; Tian, Y; Zhao, YY; Xue, C; Zhan, JH; Liu, L; He, XB; Zhang, L

Zhang, L (reprint author), Sun Yat Sen Univ, Canc Ctr,State Key Lab Oncol South China, Guangdong Key Lab Nasopharyngeal Carcinoma Diag &, Collaborat Innovat Ctr Canc Med, Guangzhou 510060, Guangdong, Peoples R China.; Zhang, L (reprint author), Sun Yat Se

CANCER COMMUNICATIONS, 2018; 38 ():

Abstract

Background: Tumor hypoxia is considered an important factor in metastasis and disease relapse. Evofosfamide is a hypoxia-activated prodrug that select......

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