Targeting sphingosine kinase 1/2 by a novel dual inhibitor SKI-349 suppresses non-small cell lung cancer cell growth

Xue, YH; Jiang, KQ; Ou, L; Shen, MJ; Yang, Y; Lu, JJ; Xu, WH

Xu, WH (通讯作者),Soochow Univ, Affiliated Hosp 2, Dept Thorac Surg, Suzhou, Peoples R China.;Lu, JJ (通讯作者),Jiangsu Univ, Affiliated Kunshan Hosp, Dept Radiotherapy & Oncol, Kunshan, Peoples R China.

CELL DEATH & DISEASE, 2022; 13 (7):

Abstract

Sphingosine kinase 1 (SphK1) and sphingosine kinase (SphK2) are both important therapeutic targets of non-small cell lung cancer (NSCLC). SKI-349 is a......

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